| Rank Player | Opponent |
|---|---|
| 1. D. Adams GB WR | JAC |
| 2. A. Kamara NO RB | SF |
| 3. A. Jones GB RB | JAC |
| 4. K. Allen LAC WR | @MIA |
| 5. A. Brown TEN WR | IND |
| 6. D. Cook MIN RB | @CHI |
| 7. D. Hopkins ARI WR | BUF |
| 8. D. Metcalf SEA WR | @LAR |
| 9. D. Henry TEN RB | IND |
| 10. N. Chubb CLE RB | HOU |
| 11. A. Robinson CHI WR | MIN |
| 12. W. Fuller HOU WR | @CLE |
| 13. J. Robinson JAC RB | GB |
| 14. C. Kupp LAR WR | SEA |
| 15. B. Aiyuk SF WR | NO |
| 16. T. Fulgham PHI WR | @NYG |
| 17. J. Jacobs LV RB | DEN |
| 18. S. Diggs BUF WR | @ARI |
| 19. A. Thielen MIN WR | @CHI |
| 20. D. Waller LV TE | DEN |
| 21. T. Lockett SEA WR | @LAR |
| 22. B. Cooks HOU WR | @CLE |
| 23. J. Jeudy DEN WR | @LV |
| 24. R. Woods LAR WR | SEA |
| 25. C. Godwin TB WR | @CAR |
| 26. T. Boyd CIN WR | @PIT |
| 27. D. Moore CAR WR | TB |
| 28. M. Thomas NO WR | SF |
| 29. T. McLaurin WAS WR | @DET |
| 30. K. Hunt CLE RB | HOU |
| 31. J. Conner PIT RB | CIN |
| 32. M. Evans TB WR | @CAR |
| 33. M. Sanders PHI RB | @NYG |
| 34. T. Hockenson DET TE | WAS |
| 35. R. Anderson CAR WR | TB |
| 36. C. Edmonds ARI RB | BUF |
| 37. C. Kirk ARI WR | BUF |
| 38. G. Bernard CIN RB | @PIT |
| 39. D. Swift DET RB | WAS |
| 40. J. Smith-Schuster PIT WR | CIN |
| 41. A. Gibson WAS RB | @DET |
| 42. C. Claypool PIT WR | CIN |
| 43. D. Johnson PIT WR | CIN |
| 44. M. Davis CAR RB (if CMC is out) | TB |
| 45. S. Shepard NYG WR | PHI |
| 46. D. Johnson HOU RB | @CLE |
| 47. A. Green CIN WR | @PIT |
| 48. A. Hooper CLE TE | HOU |
| 49. N. Fant DEN TE | @LV |
| 50. J. Jefferson MIN WR | @CHI |